Prof Brett I. Pletschke
Brett Pletschke is Professor of Biochemistry in the Department of Biochemistry and Microbiology at Rhodes University. His research interest lies in the field of applied enzymology, particularly Carbohydrate Active Enzymes (CAZymes) combined synergistically to generate bio-based products such as prebiotics, foods and feeds, and biomedical products. He has focussed on enzyme immobilization to enhance enzyme stability, reusability and process control. Thus xylanases and mannanases have been immobilized to produce prebiotic xylo- and manno-oligosaccharides, to enhance feed utilization by monogastric animals. Another line or research involves enzyme inhibitors from kelp (brown seaweed), as potential treatment for diabetes, obesity and cancer.